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Yong Zhang

Assistant Researcher

  • Tel: +8613761558463
  • Email: yzhang2011@sjtu.edu.cn
  • Address:
  • Lab Web: https://enzyme.sjtu.edu.cn/en/

Selected Publications

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    Yumeng Tan#, Yong Zhang#, Yunbin Han, Hao Liu, Haifeng Chen, Fuqiang Ma, Stephen G Withers, Yan Feng, Guangyu Yang* Directed evolution of an α1,3-fucosyltransferase using a single-cell  ultrahigh-throughput screening method. Science Advances, 2019,5 (10) eaaw8451 (# Contributed  equally)

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    Liuqing Chen, Qing Chang, Guangyu Yang, Yong Zhang*, Yan Feng* Structure of an Endogalactosylceramidase from Rhodococcus hoagii 103S Reveals the Molecular Basis of its Substrate Specificity. Journal of Structural Biology, 2019, 208(3)107393 (*Co-corresponding author)

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    Liang Yin, Xiang Guo, Lu Liu, Yong Zhang*, Yan Feng*. Self-Assembled Multimeric-Enzyme Nanoreactor for Robust and Efficient Biocatalysis. ACS Biomater. Sci. Eng., 2018, 4 (6), 2095–2099 (*Co-corresponding author)

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    Md Anarul Hoque#, Yong Zhang#, Liuqing Chen, Guangyu Yang, Mst Afroza Khatun, Haifeng Chen,Liu Hao, Yan Feng*, Stepwise Loop Insertion, Strategy for Active Site emodeling to Generate Novel Enzyme Functions. ACS Chem. Biol., 2017, 32(27)132-137(# Contributed equally)

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    Yong Zhang, Jiao An, Guangyu Yang, Xiaofei Zhang, Yuan Xie, Liuqing Chen, Yan Feng*. Structure features of GH10 xylanase from Caldicellulosiruptor bescii: implication for its thermophilic adaption and substrate binding preference. Acata Bioch. Bioph. Sin., 2016, 56(7). 56-67

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    Yong Zhang; Jian Bao; Xinxian Deng; Wan He; Jiajun Fan; Lei Fu*. Synthesis, biological evaluation and molecular docking of 2-phenyl- benzo[d] oxazole- 7-carboxamide derivatives as potential Staphylococcus aureus sortaseA inhibitors. Bioorg Med Chm Lett., 2016, 34(3). 21-28

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    Wan He#, Yong Zhang#, Jian Bao, Xinxian Deng, Jennifer Batara,Shawn Casey, Faqin Jiang*, Lei Fu*, Synthesis, biological evaluation and molecular docking analysis of 2-phenyl-benzofuran-3-carboxamide as a potential inhibitors of Sortase A. Bioorg & Med Chem. , 2016, 217(25)1341~1351 (# Contributed equally)

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    Ang Li, Yong Zhang*, Che Wang, Geng Wu*,Zhenchun Wang, Purification, molecular cloning, and antimicrobial activity of peptides from the skin secretion of the black-spotted frog, Rana nigromaculata. World J. Microbiol. Biotechnol., 2013, 32(2): 401-19 (*Co-corresponding author)

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    Seema Irani, Joshua Mayfield, Yong Zhang, Wendy L. Matthews and Yan Jessie Zhang*,Structure of S. cerevisiae Rtr1 reveals an atypical phosphatase with novel reaction mechanism, Sci. Signal., 2016, 9(417)

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    Yong Zhang, Mengmeng Zhang and Yan Zhang*. Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue. Biochem J., 2011, 434(3):435-44.