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Zixin Deng

Chair Professor

  • Tel: +86-021-62933404
  • Email: zxdeng@sjtu.edu.cn
  • Lab Web: http://mml.sjtu.edu.cn/

Selected Publications

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    Zhang Y, Zou Y, Brock NL, Huang T, Lan Y, Wang X, Deng Z, Tang Y, Lin S. Characterization of 2-Oxindole Forming Heme Enzyme MarE, Expanding the Functional Diversity of the Tryptophan Dioxygenase Superfamily. J Am Chem Soc. 2017 Aug 30;139(34):11887-11894. doi: 10.1021/jacs.7b05517. Epub 2017 Aug 15. 

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    Gao G, Liu X, Xu M, Wang Y, Zhang F, Xu L, Lv J, Long Q, Kang Q, Ou HY, Wang Y, Rohr J, Deng Z, Jiang M, Lin S, Tao M. Formation of an Angular Aromatic Polyketide from a Linear Anthrene Precursor via Oxidative Rearrangement. Cell Chem Biol. 2017 Jul 20;24(7):881-891.e4. doi: 10.1016/j.chembiol.2017.06.008. Epub 2017 Jul 14. 

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    Yang Y, Xu G, Liang J, He Y, Xiong L, Li H, Bartlett D, Deng Z, Wang Z, Xiao X. DNA Backbone Sulfur-Modification Expands Microbial Growth Range under Multiple Stresses by its anti-oxidation function. Sci Rep. 2017 Jun 14;7(1):3516. doi: 10.1038/s41598-017-02445-1. 

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    Zheng X, Cheng Q, Yao F, Wang X, Kong L, Cao B, Xu M, Lin S, Deng Z, Chooi YH, You D. Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4135-4140. doi: 10.1073/pnas.1701361114. Epub 2017 Apr 3. 

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    Xu Z, Wang Y, Chater KF, Ou HY, Xu HH, Deng Z, Tao M. Large-Scale Transposition Mutagenesis of Streptomyces coelicolor Identifies Hundreds of Genes Influencing Antibiotic Biosynthesis. Appl Environ Microbiol. 2017 Mar 2;83(6). pii: e02889-16. doi: 10.1128/AEM.02889-16. Print 2017 Mar 15. 

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    Wang Y, Tao Z, Zheng H, Zhang F, Long Q, Deng Z, Tao M. Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy. Metab Eng. 2016 Nov;38:418-426. doi: 10.1016/j.ymben.2016.10.005. Epub 2016 Oct 13. 

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    Li N, Wang H, Li L, Cheng H, Liu D, Cheng H, Deng Z. Integrated Approach To Producing High-Purity Trehalose from Maltose by the Yeast Yarrowia lipolytica Displaying Trehalose Synthase (TreS) on the Cell Surface. J Agric Food Chem. 2016 Aug 10;64(31):6179-87. doi: 10.1021/acs.jafc.6b02175. Epub 2016 Jul 29. 

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    Xu M, Wang Y, Zhao Z, Gao G, Huang SX, Kang Q, He X, Lin S, Pang X, Deng Z, Tao M. Functional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp. Appl Environ Microbiol. 2016 Sep 16;82(19):5795-805. doi: 10.1128/AEM.01383-16. Print 2016 Oct 1. 

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    Huang T, Li L, Brock N, Deng Z, Lin S. Functional Characterization of PyrG, An Unusual NRPS Module from Pyridomycin Biosynthetic Pathway. Chembiochem. 2016 May 20. doi: 10.1002/cbic.201600156. [Epub ahead of print] 

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    Wang H, Li L, Zhang L, An J, Cheng H, Deng Z. Xylitol production from waste xylose mother liquor containing miscellaneous sugars and inhibitors: one-pot biotransformation by Candida tropicalis and recombinant Bacillus subtilis. Microb Cell Fact. 2016 May 16;15:82. doi: 10.1186/s12934-016-0480-0.